Medication
We can evaluate the drugs in this group, also called phlebotropic drugs, under two headings according to the development mechanisms of the disease:
- Before the microcirculation is impaired, only those that affect the tension changes in the vein wall
- Drugs that are effective on microcirculatory disorders
Two mechanisms are responsible for pain before visual changes occur and microcirculation is disturbed. The first is changes in venous wall tension, which occurs with increased pressure in the wall as a result of valve insufficiency and venous hypertension. The second is the picture due to oxygen deficiency that occurs with changes in the media layer, which is the middle layer of the 3 layers that make up the vessel wall, and in the vessels we call the vasa vasorum, which feeds the vein's own tissue. When it comes to microcirculatory disorders, microcirculation will be disrupted in parallel with long-standing valve insufficiency and increased venous pressure, advanced insufficiency and obstructions will disrupt the microcirculation, that is, microcirculation, and will cause complaints such as edema, night cramps, restless legs to be added to your complaints.
In the disease I tried to briefly talk about the formation mechanism; In fact, one of the most important factors to be aware of is that none of the complaints of venous insufficiency, that is, venous insufficiency, are specific to the disease. Whether it's pain, edema, cramps, itching; None of these are seen only in venous insufficiency, there are tens and hundreds of reasons. For this reason, in fact, it does not have many features in the diagnosis and maintenance of the disease.
As a result, the purpose of drugs in this group is:
- Increasing the vein wall tension
- To reduce ponding and regulating micro-circulation.
The drugs in this group, whose effects start within 15 days of starting the treatment, are generally drugs that can be used for a long time with negligible side effects. However, do not forget; They do not have any effect on stopping or regressing the varicose veins. It will only slightly reduce your daily complaints.
